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Anthrax is an American heavy metal band from New York City, founded in 1981 by guitarists Scott Ian and Danny Lilker. The band was one of the most popular of the 1980s thrash metal scene. When thrash metal began to gain a major following in the mid-to-late 1980s, Anthrax were dubbed one of the "big four" of thrash metal alongside Metallica, Megadeth and Slayer.